The PPFIBP1 antibody - N-terminal region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Guinea Pig, Horse, Porcine, Rabbit, and Zebrafish/Fish antigen. The PPFIBP1 antibody - N-terminal region has been validated for the following applications: Western Blot.
Description
This is a rabbit polyclonal antibody against PPFIBP1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported